| Round 1 |
| Saturday, 2 November 2024 |
| 1 | Birkenhead Park Wanderers (2nd XV) | v | Bye |
| 2 | Eagle | 5 | 34 | Sale FC Vikings |
| 3 | Anselmians 2nd XV | v | Bye |
| 4 | Sandbach 2nd XV | v | Bye |
| 5 | Aldwinians 2nd XV | 15 | 20 | Eccles 2nd XV |
| 6 | Vale of Lune 2nd XV | Away Walkover | Firwood Waterloo 2nd XV |
| 8 | Preston Grasshoppers 3rd XV | v | Bye |
| Saturday, 9 November 2024 |
| 7 | Stockport 2nd XV | 83 | 5 | Kendal 2nd XV |
| Round 2 |
| Saturday, 25 January 2025 |
| Anselmians 2nd XV | 22 | 26 | Sandbach 2nd XV |
| Birkenhead Park Wanderers (2nd XV) | 14 | 21 | Sale FC Vikings |
| Eccles 2nd XV | 57 | 7 | Firwood Waterloo 2nd XV |
| Saturday, 1 February 2025 |
| Stockport 2nd XV | Home Walkover | Preston Grasshoppers 3rd XV |
| Round 3 |
| Saturday, 29 March 2025 |
| Sandbach 2nd XV | 27 | 43 | Sale FC Vikings |
| Eccles 2nd XV | 26 | 47 | Stockport 2nd XV |
| Round 4 |
| Saturday, 3 May 2025 |
| Sale FC Vikings | 43 | 18 | Stockport 2nd XV |