Fixtures & Results
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| Sunday, 05/09/2021 - Senior G Preliminary |
| Transition Week | v | Ashton-Under-Lyne Senior U18 Colts |
| Sunday, 05/09/2021 - Senior F Preliminary |
| Transition Week | v | Aldwinians Senior U18 Colts |
| Sunday, 05/09/2021 - Senior E Preliminary |
| Transition Week | v | Bolton Senior U18 Colts |
| Sunday, 05/09/2021 - Senior G Preliminary |
| Transition Week | v | Ashton-Under-Lyne Senior U18 Colts |
| Sunday, 12/09/2021 - Senior E Preliminary |
| Crewe & Nantwich Senior U18 Colts | v | Transition Week |
| Sunday, 12/09/2021 - Senior F Preliminary |
| Tyldesley Senior U18 Colts | v | Transition Week |
| Sunday, 12/09/2021 - Senior G Preliminary |
| Fleetwood Senior U18 Colts | Liquidated Fixture | Transition Week |
| Sunday, 12/09/2021 - Senior G Preliminary |
| Fleetwood Senior U18 Colts | Liquidated Fixture | Transition Week |
| Sunday, 19/09/2021 - Senior F Preliminary |
| Transition Week | v | Glossop Senior U18 Colts |
| Sunday, 19/09/2021 - Senior E Preliminary |
| Transition Week | v | Preston Grasshoppers Senior U18 Colts |
| Sunday, 19/09/2021 - Senior G Preliminary |
| Transition Week | v | Blackburn Senior U18 Colts |
| Sunday, 19/09/2021 - Senior G Preliminary |
| Transition Week | v | Blackburn Senior U18 Colts |
| Sunday, 03/10/2021 - Senior F Preliminary |
| Widnes Senior U18 Colts | v | Transition Week |
| Sunday, 03/10/2021 - Senior G Preliminary |
| New Brighton Senior U18 Colts | v | Transition Week |
| Sunday, 03/10/2021 - Senior E Preliminary |
| Rochdale Senior U18 Colts | v | Transition Week |
| Sunday, 17/10/2021 - Senior F Preliminary |
| Transition Week | v | Kendal Senior U18 Colts |
| Sunday, 17/10/2021 - Senior E Preliminary |
| Transition Week | v | Newcastle (Staffs) Senior U18 Colts |
| Sunday, 17/10/2021 - Senior G Preliminary |
| Transition Week | v | Bury Senior U18 Colts |
| Sunday, 17/10/2021 - Senior G Preliminary |
| Transition Week | v | Bury Senior U18 Colts |